产品货号：
Z17686
中文名称：
GLUD1/2抗体
英文名称：
Anti-GLUD1/2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-GLUD1/2 Antibody |
| 指标别名 | GLUD1;GLUD;mitochondrial;GDH 1;GLUD2;GLUDP1;GDH 2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,IF,ICC/IF,FCM,ELISA |
| 基因名称 | GLUD1/GLUD2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human GLUD1/2 recombinant protein (Position:S54-A553). |
| 实际分子量 | 54KD |
| 成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | This gene encodes glutamate dehydrogenase,which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.This enzyme has an important role in regulating amino acid-induced insulin secretion.It is allosterically activated by ADP and inhibited by GTP and ATP.Activating mutations in this gene are a common cause of congenital hyperinsulinism.Alternative splicing of this gene results in multiple transcript variants.The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase.Related pseudogenes have been identified on chromosomes 10,18 and X. |
| Uniprot ID | P00367/P49448 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P) and ICC. |
| 基因名全称 | glutamate dehydrogenase 1/2 |
| 蛋白名全称 | Glutamate dehydrogenase 1/2,mitochondrial |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunofluorescence (IF) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells ELISA 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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